Pharmacology
Mechanism of Action
Retinoid: appears to affect expression of genes that modulate cell (eg, epidermal) differentiation, proliferation, and inflammation, leading to normalization of keratinocyte differentiation and a reduction in cellular hyperproliferation and inflammation
Absorption
<1% systemically absorbed
Metabolism
Hydrolyzed to its active metabolite, tazarotenic acid
Elimination
Half-Life: 18 hr