Nexium 20 mg

Esomeprazole 20 mg

Administration
Oral Administration
If unable to swallow capsule whole, capsule can be opened, emptied on applesauce, mixed, and swallowed immediately

IV Compatibilities
Solution: NS, LR, D5W

IV Preparation
IV injection

  • Reconstitute contents of 1 vial with 5 mL NS
  • Store at room temp (no refrigeration required) and administer within 12 hr
Intermittent IV infusion

  • Reconstitute 1 vial with 5 mL NS, LR, or D5W
  • Further dilute to 50 mL
  • Store at room temp (no refrigeration required) and administer within 12 hr if diluted in NS or LR, and within 6 hr if diluted in D5W
Continuous IV infusion

  • Reconstitute two 40 mg vials with 5 mL each of 0.9% NaCl
  • Further dilute the 2 reconstituted vials in 100 mL 0.9% NaCl
IV Administration
IV injection

  • Injection: Over no less than 3 min
Intermittent IV infusion

  • Infuse over 10-30 min regardless of amount
  • Flush IV line with NS, LR, or D5W prior to and after administration
  • Do not administer with any other drugs
Continuous IV infusion

  • Administer initial 80 mg IV dose over 30 min, THEN follow with
  • Continuous IV infusion of 8 mg/hr for total treatment duration of 72 hr
References