Naltrexone HCL 50 mg
More than 10%
Injection site reaction (69%; includes bruising, induration, nodules, pain, pruritus, swelling, tenderness)
Nausea (33%)
Headache (25%)
Decreased appetite (14%)
Insomnia (14%)
Vomiting (14%)
Diarrhea (13%)
Dizziness (13%)
Upper respiratory tract infection (URTI) (13%)
Anxiety (12%)
Arthralgia (12%)
Increased creatine phosphokinase (11%)
Pharyngitis (11%)
1-10%
Depression (8%)
Muscle cramps (8%)
Back pain (6%)
Rash (6%)
Dry mouth (5%)
Somnolence (4%)
Increased aspartate aminotransferase (AST) (2%)
Less than 1%Alopecia
Dyspnea
Edema
Hepatocellular injury
Increased systolic and diastolic blood pressures
Liver function abnormalities
Labored breathing
Nonspecific electrocardiographic (ECG) changes
Opiate withdrawal (mild to severe signs and symptoms, including drug craving, confusion, drowsiness, visual hallucinations, abdominal pain, vomiting, diarrhea)
Palpitation
Phlebitis
Tachycardia